Partial - Order Alignment of RNA Structures by Ethan Bromberg - Martin
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MOTIVATION Progressive Multiple Sequence Alignment (MSA) methods depend on reducing an MSA to a linear profile for each alignment step. However, this leads to loss of information needed for accurate alignment, and gap scoring artifacts. RESULTS We present a graph representation of an MSA that can itself be aligned directly by pairwise dynamic programming, eliminating the need to reduce the MS...
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تاریخ انتشار 2005